Complesso di San Firenze is one of the rarest examples of Baroque architecture in Florence. Located in the middle of the city it consists of a church and a convent dating to the 12th century. The interior of the church is decorated with Baroque sculptures, reliefs, frescoes and paintings.

The Laurentian Library in Florence, is famous as a repository of more than 11,000 manuscripts and 4,500 early printed books. Built in a cloister of the Medicean Basilica di San Lorenzo di Firenze under the patronage of the Medici pope, Clement VII, the Library was built to emphasize that the Medici family were no longer mere merchants but members of intelligent and ecclesiastical society. It contains the manuscripts and books belonging to the private library of the Medici family. The Laurentian Library was commissioned in 1523 and construction began in 1525. The Library conserves the Nahuatl Florentine Codex, the major source of pre-Conquest Aztec life. Among other well-known manuscripts in the Laurentian Library are the sixth-century Syriac Rabula Gospels; the Codex Amiatinus, which contains the earliest surviving manuscript of the Latin Vulgate Bible; and the fragmentary Erinna papyrus containing poems of the friend of Sappho.

The octagonal Cappella dei Principi surmounted by a tall dome, 59 m. high, that is the distinguishing feature of San Lorenzo when seen from a distance, stands centrally sited with respect to the nave, to which it provides the equivalent of an apsidal chapel. Its entrance is from the exterior, in Piazza Madonna degli Aldobrandini, and through the low vaulted crypt planned by Bernardo Buontalenti before plans for the chapel above were made. It was designed by Matteo Nigetti, following some sketches tendered to an informal competition of 1602 by Don Giovanni de' Medici, the natural son of Cosimo I, Grand Duke of Tuscany, which were altered in the execution by the aged Buontalenti; thus, a true expression of court art, it was the result of collaboration among designers and patrons.

The church of San Gaetano, also known as Santi Michele e Gaetano, on the Piazza Antinori, is one of the most important examples of the Baroque style in Florence, a city better known for its Renaissance architecture. The façade, with its sculptural decorations, is highly atypical for Florentine churches, which had a predilection for geometrically ornamented façades. The church was built for the Theatine order, who obtained funding from the noble families in Florence, including the Medicis. Cardinal Carlo de' Medici was particularly concerned with the work, and his name is inscribed on the façade. Building took place between 1604 and 1648. The original designs were by Bernardo Buontalenti but a number of architects had a hand in building it, each of whom changed the design. The two most important architects were Matteo Nigetti and Gherardo Silvani.

Palazzo Corsini al Parione is one of the most magnificent private palaces in Florence. The structure is entirely Baroque and features elliptical windows, staircases decorated with statues and large columns. The interior is decorated with many frescoes, paintings and genuine furniture.

The All-Saints Church is a Franciscan church in Florence. Founded by the lay order of the Umiliati, the church was dedicated to all the saints and martyrs, known and unknown. It was completed during the 1250s, but almost completely rebuilt on Baroque designs of Bartolomeo Pettirossi, about 1627, with a façade - by Matteo Nigetti - that conserved the grand glazed terracotta lunette in the manner of the Della Robbia, now attributed to Benedetto Buglioni, over the doorway: Ognissanti was among the first examples of Baroque architecture to penetrate this Renaissance city. In the interior, the Baroque remodelling, which provided a completely rebuilt apse with a pietre dure high altar and a sotto in su perspective on the vaulted nave ceiling, preserved quattrocento frescoes in the nave chapels, by Ghirlandaio and Botticelli, who is buried in the church near his beloved Simonetta Vespucci.

San Frediano in Cestello is a church in the Oltrarno section of Florence. The name cestello derives from the Cistercians who occupied the church in 1628. Previously the site had a 1450s church attached to the cloistered Carmelite convent of Santa maria degli Angeli. In 1680-1689, the church was rebuilt on the designs of Gherardo Silviani and Giulio Cerutti. The imposing cupola and bell tower added in 1689 by Antonio Maria Ferri. The interior is frescoed with a Glory of the Magdalen and Virtue (1702–1718) by Antonio Domenico Gabbiani. The cloisters contain a statue of St. Maria Maddalena de' Pazzi (1726) by Antonio Montauti and a St. Bernard of Clairvaux defeats the devil (1702) by Giuseppe Piamontini (1702). The latter cloister was designed by Gherardo and Piefrancesco Silvani.

Cappella Corsini is a chapel in the Santa Maria del Carmine church in Florence. It was built in the 17th century by the Corsini family. With its rich decorations and sculptures it is considered a marble of Baroque architecture.