Old North Church (officially, Christ Church in the City of Boston), at 193 Salem Street, in the North End of Boston, is the location from which the famous "One if by land, and two if by sea" signal is said to have been sent. This phrase is related to Paul Revere's midnight ride, of April 18, 1775, which preceded the Battles of Lexington and Concord during the American Revolution. It is the oldest active church building in Boston and is a National Historic Landmark. Inside the church is a bust of George Washington, which the Marquis de Lafayette reportedly remarked as the best likeness of him he had ever seen. Old North Church was built in 1723, and was inspired by the works of Christopher Wren, the British architect who was responsible for rebuilding London after the Great Fire. Eight change ringing bells at Old North Church were cast in Gloucester, Massachusetts in 1744 and hung in 1745.

The Old West Church at 131 Cambridge Street, is a historic church located in the West End of Boston, built in 1806 to designs by architect Asher Benjamin. Old West's preaching played a major role in American history. Jonathan Mayhew, the church's second Congregational pastor, coined the phrase, "no taxation without representation" in a sermon in Old West. Today's Old West Church is thus the second church on the site. As in the architect's earlier Charles Street Meeting House (1804), its three-and-a-half story brick entry tower is crowned with a cupola; the whole tower projects outward somewhat from the church hall behind. Four shallow brick pilasters, each two stories high and trimmed with white wood, separate the three entry doors. Each door is echoed with window above it. On the final half-story beneath the cupola are clocks on each face of the tower, each adorned with a light swag. On the back wall, the original central pulpit window has been filled in with brickwork.

King's Chapel is "an independent Christian unitarian congregation affiliated with the Unitarian Universalist Association" that is "Unitarian Christian in theology, Anglican in worship, and congregational in governance." It is housed in what was formerly called "Stone Chapel", an 18th century structure at the corner of Tremont Street and School Street in Boston, Massachusetts. In 1749, construction began on the current stone structure, which was designed by Peter Harrison and completed in 1754. Inside, the church is characterized by wooden columns with Corinthian capitals that were hand-carved by William Burbeck and his apprentices in 1758. The current uniform appearance of the pews dates from the 1920s. Music has long been an important part of King's Chapel, which acquired its first organ in 1723. The present organ, the sixth installed in King's Chapel, was built by C. B. Fisk in 1964. The burying ground at King's Chapel is the site of the graves of many historic figures.

The Park Street Church (built 1810) in Boston, Massachusetts is an active Conservative Congregational Church at the corner of Tremont Street and Park Street. Park Street church's steeple rises to 217 feet, and remains a landmark visible from several Boston neighborhoods. The steeple is seen as the terminus of both Columbus Avenue and Tremont Street, two of Boston's radial avenues. The church is adjacent to the historic Granary Burying Ground. The cornerstone of the church was laid on May 1 and construction was completed by the end of the year, under the guidance of Peter Banner (architect), Benajah Young (chief mason) and Solomon Willard (woodcarver). Banner took inspiration from several early pattern books, and his design is reminiscent of a London church by Christopher Wren. The church became known as "Brimstone Corner", in part because of the missionary character of its preaching, and in part because of the storage of gunpowder during the War of 1812.

The Church of the Covenant (a merger of Central Congregational Church and First Presbyterian Church) is a Boston, Massachusetts, landmark, built in 1865-1867 by the Central Congregational Church and now affiliated with the Presbyterian Church and the United Church of Christ. Built of Roxbury puddingstone in Gothic Revival style it was one of the first churches to relocate in the new Back Bay and was built largely with funds donated by Benjamin E. Bates, an industrialist who founded Bates College. Designed by Richard M. Upjohn, the son and partner of Richard Upjohn, who insisted on "a high Gothic edifice ... which no ordinary dwelling house would overtop." It has a 240-foot high steeple, that overtops the Bunker Hill Monument. In the 1890s the sanctuary was redecorated by Tiffany Glass and Decorating Co. with stained-glass windows and mosaics and an electric-light chandelier designed by Tiffany's Jacob Adolphus Holzer for the World's Columbian Exhibition, Chicago, 1893.

First Baptist Church (or "Brattle Square Church") is a historic Baptist church established in 1665. It first met secretly on Noddle's Island and then in the North End of Boston, Massachusetts. Since 1882 it has been located at the corner of Commonwealth Avenue and Clarendon Street in the Back Bay. Featuring ivy-covered walls and a prominent tower with distinctive carvings by Frederic Auguste Bartholdi (sculptor of the Statue of Liberty) representing four sacraments, with faces of famous Bostonians (including Longfellow and Hawthorne), Abraham Lincoln, and Bartholdi's friends of that era.(including 'Garibaldi'). This building highlights many of the Richardsonian Romanesque qualities that would later be shown in the nearby Trinity Church, one of Richardson's masterpieces. The Baptist Church's tower can clearly be seen as part of Boston's skyline when viewed from the Cambridge side of the Charles river.

Old South Church is a church of the United Church of Christ in Boston, Massachusetts. The church building was designed between 1870 and 1872 by the Boston architectural firm of Cummings and Sears in the Venetian Gothic style. The style follows the precepts of the British cultural theorist and architectural critic John Ruskin (1819–1900) as outlined in his treatise The Stones of Venice. Old South Church in Boston remains one of the most significant examples of Ruskin's influence on American architecture. A tall tower, or campanile is the trademark feature of Old South and is visible from several Boston neighborhoods. The tower, on the western end of the church, rises to a height of 246' and houses the church's 2020 pound bell. The interior of Old South is exuberant yet quietly modulates the mix of rich materials: highly carved Italian cherry woodwork, limestone, stenciled plaster, and stained glass.

After its former site on Summer Street burned in the Great Boston Fire of 1872, the current church complex was erected under the direction of Rector Phillips Brooks, one of the best-known and most charismatic preachers of his time. The church and parish house were designed by Henry Hobson Richardson and construction took place from 1872 to 1877, when the complex was consecrated. Situated on Copley Square in Back Bay, Trinity Church is the building that established Richardson's reputation. It is the birthplace and archetype of the Richardsonian Romanesque style, characterized by a clay roof, polychromy, rough stone, heavy arches, and a massive tower. The building's plan is a modified Greek Cross with four arms extending outwards from the central tower, which stands 211 ft tall. Trinity Church is the only building from the original 1885 list still included in the American Institute of Architects's current top ten list.

In Boston’s Back Bay area stands a 14 acre complex open to visitors; it is the administrative headquarters and the First Church of Christ Scientist Mother Church.

The Christian Science movement was founded by Mary Baker Eddy in 1879 and the First Church was consecrated in 1894. The Mother Church Extension was built in the Byzantine style in 1906. The lower half of the walls in the interior of the church are extensively decorated in mosaic, above which are elegant stencilled Italian-style frescoes. The floor is Italian marble. The church boasts of having the world’s largest pipe organ, built in 1952 by the Aeolian-Skinner Company.

In 1935 the Christian Science Centre installed a magnificent Mapparium by Rand McNally. The Mapparium is a stained glass globe showing the “political world” of that time, projected by a light and sound display. Also in the complex are reading rooms where you can read or buy the Bible, bible-related material and all of Mary Baker Eddy’s writings.

In 1960 a plaza with fountains and benches was installed in the complex, which is very popular with tourists and Bostonians alike. At visit to the church and the complex is a great way of spending and afternoon.