Exchange and Provost, also known as the Old Exchange & Provost Dungeon, Custom House and Half-Moon Battery, and The Exchange, was built in 1767. The National Park Service describes: "...the structure has served as a customhouse, merchantile exchange, military prison and barracks, and post office. In 1790, the State Legislature met here to ratify the new State Constitution. The building was badly damaged by Union artillery fire during the Civil War and the great earthquake of 1886; it was repaired after each occasion." It was declared a National Historic Landmark in 1973. The South Carolina Department of Archives and History summary is here. The Old Exchange Building is owned by the South Carolina Society of the Daughters of the American Revolution, who operate guided costumed tours that include all three floors of the building. The Provost Dungeon features animatronic figures that tell stories of pirates and colonial days.

Old Slave Mart Museum is a history museum located in a building constructed in 1859. The museum features some fascinating exhibitions on the tragic experience of African Americans in South Carolina. The museum also highlights the personal experiences of former slave families.

The Powder Magazine is a gunpowder magazine and museum in Charleston, and the oldest surviving public building in the former Province of Carolina. It was erected in 1713 by colonial settlers as a place to safely store and centralize their gunpowder supplies. It was also involved in the 1780 siege of Charleston. The Powder Magazine was declared a National Historic Landmark in 1989. It has operated as a museum since the early 1900s, although extensive renovations have since been conducted. The National Society of the Colonial Dames of America is the current operator of the museum, which includes historic artifacts and displays about the building during the Colonial and American Revolution periods. Each wall of the building boasts a large arch. The walls get thinner as they reach the top of the arch, changing from three feet thick, near the ground, to just a few inches thick near the top.

The Jewish Heritage Collection is a very interesting archives located in Special Collections at the College's Addlestone Library. It shows 300 years of Jewish life in the southern United States. The exhibitions were established in 1995 and have been enriched by documents, photographs, and other memorabilia relating to the Jews. The museum is taken care of by the Jewish Historical Society of South Carolina.

Karpeles Manuscript Museum is the world’s largest museum of original documents and manuscripts. The museum was founded in 1983 by David and Marsha Karpeles. It is located inside the St. James Methodist Church. This museum is really fascinating and unique.

Citadel Archives and Museum is located on the grounds of the Military College of South Carolina and tells the history of the college since its foundation in 1842 till the present times. It has very interesting and exceptional exhibitions and memorabilia.