The Forte di Belvedere or Fortezza di Santa Maria in San Giorgio del Belvedere is a fortification in Florence. It was built by Grand Duke Ferdinando I de' Medici during the period 1590–1595, with Bernardo Buontalenti as the designer, to protect the city and its rule by the Medici family. In particular, it was used to hold the Medici treasury. The design and construction of the Fort were entrusted to architect Bernardo Buontalenti, the chief architect for both Cosimo I and his son, Ferdinando. The Fort served many purposes: to protect the center of government in Florence, the Pitti Palace; to protect the south end of the city of Florence and the Oltrarno district; to demonstrate the power of the Medici family; and finally to provide a shelter for the Grand Duke if the city came under attack. The fort was connected to Palazzo Vecchio via the Vasari Corridor over Ponte Vecchio, passages in the Pitti Palace and paths through Boboli Gardens.

The Palazzo Pitti is a vast mainly Renaissance palace in Florence. It is situated on the south side of the River Arno, a short distance from the Ponte Vecchio. The core of the present palazzo dates from 1458 and was originally the town residence of Luca Pitti, an ambitious Florentine banker. The palace was bought by the Medici family in 1549 and became the chief residence of the ruling families of the Grand Duchy of Tuscany. It grew as a great treasure house as later generations amassed paintings, plates, jewelry and luxurious possessions. In the late 18th century, the palazzo was used as a power base by Napoleon, and later served for a brief period as the principal royal palace of the newly united Italy. Today, it houses several minor collections in addition to those of the Medici family, and is fully open to the public.

Palazzo Vecchio is an amazing palace and the town hall of Florence. It was built in the 14th century to represent the power and wealth of the city. It was the official residence of the ruling Medici family for a long time until they moved to the Pitti palace. Palazzo Vecchio houses an impressive collection of works of art from the personal collection of the Medicis.

The Palazzo Medici, also called the Palazzo Medici Riccardi for the later family that acquired and expanded it, is a Renaissance palace located in Florence. The palace was designed by Michelozzo di Bartolomeo for Cosimo de' Medici, of the Medici family, and was built between 1445 and 1460. It was well known for its stone masonry that includes rustication and ashlar. The tripartite elevation was used here as a revelation of the Renaissance spirit of rationality, order, and classicism of human scale. This tripartite division is emphasized horizontal stringcourses that divide the building into stories of decreasing height. This makes the building seem lighter as the eye moves up to the extremely heavy cornice that caps and clearly defines the building's outline.

The Villa Medici is an architectural complex centred on the villa whose gardens are contiguous with the larger Borghese gardens, on the Pincian Hill next to Trinità dei Monti in Rome. The Villa Medici, founded by Ferdinando I de' Medici, Grand Duke of Tuscany and now property of the French State, has housed the French Academy in Rome since 1803. A musical evocation of its garden fountains features in Ottorino Respighi's Fontane di Roma. In ancient times, the site of the Villa Medici was part of the gardens of Lucullus, which passed into the hands of the Imperial family with Messalina, who was murdered in the villa. Among the striking assemblage of Roman sculptures in the villa were some one hundred seventy pieces bought from two Roman collections that had come together through marriage, the Capranica and the della Valle collections.

The Villa Medici at Careggi is a patrician villa in the hills near Florence. The villa was among the first of a number of Medici villas, notable as the site of the Platonic academy founded by Cosimo de' Medici, who died at the villa in 1464. Like most villas of Florentine families, the villa remained a working farm that helped render the family self-sufficient. Cosimo's architect there, as elsewhere, was Michelozzo, who remodelled the fortified villa which had something of the character of a castello. Its famous garden is walled about, like a medieval garden, overlooked by the upper-storey loggias, with which Michelozzo cautiously opened up the villa's structure. Michelozzo's Villa Medici in Fiesole has a more outward-looking, Renaissance character.

Villa La Petraia is a Medici villa not far from Florence. It is considered one of the most beautiful and famed villas around Florence. In the first half of the 17th century, the villa passed to one of the Medici family members who enriched it with a valuable collection of paintings and frescoes.

Villa di Castello is located very close to another Medici residence - Villa La Petraia. It is famous for its magnificent gardens, comparable only with those of Boboli at the Pitti palace, also a Medici residence.