The Castle of Saint George is situated on the highest hill of Lisbon and offers a great view of the city. The castle dates from medieval times and is located in the Alfama district. Alfama used to be the district of Lisbon's Jewish and Muslim communities. It was also the residence of Portuguese kings until the 16th century.

The Church of Sao Domingos is located in a quiet square to the east of the Rossio. It was historical site where sentences were pronounced during the inquisition against heretics.
There have been churches on the site of the present Church of Sao Domingos since the 13th Century. Relics from many earlier churches that were destroyed by fire or earthquakes are found in the interiors. Before the devastating earthquake of 1755, it was the site of a Dominican monastery and convent. After the 1755 earthquake, the present church was constructed around the original chapel portal and is one of the finest examples of Baroque architecture in Lisbon.
The design of the present Church of Sao Domingos is the work of architect, Carlos Mardel. The façade and chancel are by Joao Frederico Ludovice. The structure was again damaged by a fire in 1950 and has since been restored partially. Visitors can still see the burnt pillars inside the church. Despite the damage, it still has a beautiful high altar with red columns that support an ornate sculpture of the Holy Trinity. The church is frequented by the African community of Lisbon and locals come to a small bar near the church for a popular local cherry brandy called Gingingha.

The Rossio Square is one of the main squares in Lisbon from the middle ages. It is a popular meeting place for locals and visitors to Lisbon for centuries and some of the surrounding cafes date back to the 18th century.
Rossio is the popular name for the Pedro IV Square in honor of Pedro IV, the King of Portugal and the first Emperor of Brazil. His statue is placed on a column at the center of the square. Rossio means commons or commonly owned terrain. In 1450, the Palace of Estaus was built at the northern part of the square. The palace was used at first to receive foreign dignitaries and later became the seat of the inquisition. Once inquisition sentences were pronounced, those declared as heretics were burned at stake in public at the Rosseo. It has also been the site of bullfights, revolts and celebrations.
Today, the Rosseo square is a pleasant place where locals and visitors come for a stroll, for browsing in the surrounding quaint shops or for a drink at the many cafes that offer outdoor seating. It is paved with cobblestones in wave patterns, a paving style used in Portugal and many of its colonies. There are two baroque fountains on either side of the square and at the site of the former inquisition palace is the Dona Maria II National Theatre.

The Praça do Comércio is situated near the Tagus River. The square is still commonly known as Terreiro do Paço, because it was the location of the Paços da Ribeira (Royal Ribeira Palace) until the building was destroyed by the great 1755 Lisbon Earthquake. After the earthquake, the square was completely remodeled as part of the rebuilding of downtown Pombaline by order of the Marquis of Pombal. The square was renamed Praça do Comércio, the Square of Commerce, to indicate its new role in the economy of Lisbon.

The Old Church of the Immaculate Conception is an ornate building that dates back to the 16th Century. It was declared a national monument in 1910 and is one of the oldest places of worship in Portugal.
The Igreja da Conceicao Velha was built on the site of a 15th century Synagogue. It was consecrated as the Church of Our Lady of Mercy. It was constructed under the orders of King Manuel I at the request of his sister Leonor of Viseu and her confessor Friar Miguel Contreiras. Leonor also founded the Order of Mercy and the church was dedicated to Our Lady of Mercy. At the time of consecration, it was the second largest church in Lisbon and the finest example of the Manueline style of architecture that combined Renaissance and Gothic designs. In 1755 the church was destroyed by the devastating earthquake and tsunami damaged many buildings in Lisbon and only the façade of the old structure was left. The present church was constructed again using the material from the ruins of the old church.
The present Igreja da Conceicao Velha has a magnificent portal with ornate figures of our Lady of Mercy and public figures like Pope Alexander VI, King Manuel I, his queen Eleanor and the figure of Leonor of Viseu at whose behest the church was built. Unlike other churches in the city, it has only one nave. The ceilings have a stucco pattern and the chancel is covered by a barrel vaulted ceiling.

The Casa dos Bicos or House of Spikes is a unique architectural gem in Lisbon. It gets its name from the pointed stone spikes that cover its façade.
The Casa dos Bicos was built under the orders of Bras de Albequerque, a wealthy merchant and son of Afonso de Albequerque, the well known Portuguese Viceroy in Goa, India. It was completed in the 16th century and is one of the most visited buildings in Lisbon. The Casa dos Bicos survived the 1755 earthquake with little damage and is regarded as an important landmark in the city. With the exception of the two upper floors, the building largely remained intact. The Municipality of Lisbon took possession in 1980 and restored it based on the original plan and drawings. The façade is covered with 1,125 diamond shaped stone spikes. It is modeled after the Palazzos of Venice with Portuguese style Manueline arched windows.
Casa Dos Bicos is not open to the public except when it hosts special exhibitions. Possession is now with the Saramago Foundation and the building is being converted into a museum dedicated to the life and works of Portuguese Nobel Laureate, Jose de Sousa Saramago. The building will host literary events and house Saramago’s extensive library.