Tampa Museum of Art, opened in 1979, has a commitment to preserve and interpret regional, national, and international works of art. This downtown museum has many themed exhibitions comprising paintings, sculptures, photography and hand-made pieces of art. Don't forget to stop by the newly opened waterfront Sono Cafe.

Built in 1926 for an estimated cost of 1.2 million dollars, the Tampa Theater was the first theater to appear in the city. Designed by architect J. Eberson, it was the first building in Tampa to have air-conditioning. It has become a cultural landmark, as it has withstood the ever-changing advances movie theaters have undergone in recent decades. The theater hosts over 600 events yearly and its incredible interior design features a nighttime sky ceiling, complete with glowing stars and floating clouds.

Sacred Heart is the oldest church in Tampa, making it a significant landmark of the city. It was dedicated and opened in 1905 and featured striking Romanesque architecture. The highlights of this church are its 70 exquisite stained glass windows which were made in the late 1800s. The interior features beautiful old icons and artifacts.

One Mack-Cali Center is one of the many skyscrapers found in Tampa. It is the 18th tallest structure in the city, with a height of 77 m. The bottom 3 garage floors are topped by a slew of well-known law practices, smaller law offices, the Law Library, and several other offices of Tampa-based companies.

Park Tower is the second oldest building in Tampa. It was built in 1973 and was the tallest structure of the city until 1981 when the One Tampa City Center was built. The building was the original home of the First Federal Bank and has now become the headquarters for Colonial bank. The tower stands 460 ft tall and has 36 floors.

Plant Hall is another landmark of the city located in the University of Tampa. The Hall was originally a famous hotel, which then transformed into Tampa University. The building was preserved due to its great history and the superb architectural design of Frederic Spaulding. The main building of the university has a style influenced by Moorish Revival architecture.